Tabimorelin

CAS: 193079-69-5

Ref. 3D-THA07969

Product Information

• Name: Tabimorelin
• Synonyms: (R)-alpha-((E)-5-Amino-N,5-dimethyl-2-hexenamido)-N-methyl-N-((R)-alpha-(methylcarbamoyl)phenethyl)-2-naphthalenepropionamide, <span class="text-smallcaps">D</smallcap>-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-<smallcap>D</span>-alanyl-N,N^α-dimethyl-, <span class="text-smallcaps">D</smallcap>-Phenylalaninamide, N-[(2E)-5-amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-<smallcap>D</span>-alanyl-N,N^α-dimethyl-, N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexen-1-yl]-N-methyl-3-(2-naphthalenyl)-<span class="text-smallcaps">D</smallcap>-alanyl-N,N^α-dimethyl-<smallcap>D</span>-phenylalaninamide, N-[(2E)-5-amino-5-methylhex-2-enoyl]-N-methyl-3-(naphthalen-2-yl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamide, Nn 703, Nnc 26-0703, Tabimorelin [INN], Unii-L51Cbe03Kf

Description

Tabimorelin is a potent analog of the endogenous hormone ghrelin. It binds to the ghrelin receptor and stimulates appetite, thereby increasing food intake and weight gain. Tabimorelin also has been shown to be effective in treating bowel disease, diabetic neuropathy, and symptoms of inflammatory bowel disease. The pharmacological effects of tabimorelin are due to its ability to bind to receptors in the gastrointestinal tract. This drug also has an effect on coordination complex formation by human liver microsomes. Tabimorelin can be used as a diagnostic tool for some types of cancer because it is not metabolized by enzymes in healthy cells, but is metabolized by enzymes in cancer cells. The use of tabimorelin as an analytical method is based on its ability to form coordination complexes with heavy metals such as mercury or lead.

• Brand: Biosynth

Chemical properties

• Molecular weight: 1,173.4 g/mol
• Formula: C₆₈H₈₄N₈O₁₀
• Purity: Min. 95%