Product Information
- N-(4-Methyl-2-thiazolyl)-2-[(6-phenyl-3-pyridazinyl)thio]-acetamide
VU0240551 is a novel, potent, and selective allosteric modulator of the GABA receptor. It has been shown to have an excitatory effect in animal models of epilepsy and depression. VU0240551 has been shown to act as an allosteric modulator of α5-containing GABAA receptors, but not α1- or α2-containing GABAA receptors. This drug also potently increased chloride transport rates in mouse hippocampal neurons without affecting sodium or potassium transport rates. It has been proposed that this drug may be used for the treatment of seizures, depression, and chronic pain.
VU0240551 is currently being evaluated for its efficacy as a therapeutic agent for the treatment of epilepsy and depression by a Phase 2 clinical trial (NCT02696679).
Chemical properties
Technical inquiry about: 3D-TKB99034 VU0240551
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.
