Product Information
Name:AZD5991
Brand:Biosynth
Description:AZD5991 is a gossypol derivative that has potent antitumor activity and is an inhibitor of the apoptosis pathway. AZD5991 inhibits the expression of MCL-1, which plays a key role in the regulation of mitochondrial membrane depolarization. It also inhibits cyclin D2, which is important for cell cycle progression, and pd-l1, which regulates T cell activation. These activities indicate that AZD5991 may be a potential anticancer agent for treatment of myeloid leukemia cells or T-cell lymphomas. The enantiomer form of AZD5991 has been shown to be more potent than the racemic mixture in inducing apoptosis in cancerous cells.
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Chemical properties
Molecular weight:672.3 g/mol
Formula:C35H34ClN5O3S2
Purity:Min. 95%
Technical inquiry about: AZD5991
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