Product Information
CC-671 is a synthetic compound that has been shown to have potent anticancer activity. It has been shown to be localized in the bladder, as well as other tissues, and to inhibit cancer stem cell growth. CC-671 inhibits multidrug resistance by blocking the ABCG2 transporter, which is responsible for efflux of chemotherapeutic drugs from cells. CC-671 also inhibits splicing by sequestering the human protein SRPK2, which is an abcg2 substrate that regulates mRNA production and protein synthesis. This inhibition leads to a decrease in cancer cell proliferation and survival.
Chemical properties
Technical inquiry about: 3D-TPC65888 CC-671
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