Product Information
- Bms-536924
BMS 536924 is a novel small molecule that is an ATP-binding cassette transporter (ABC) inhibitor. It has been shown to inhibit the ABCB1, ABCC1 and ABCG2 transporters in vitro. BMS 536924 has also been shown to increase cytosolic calcium levels in prostate cancer cells. This drug was found to induce apoptosis in insulin-stimulated glucose-6-phosphatase (IGP)-deficient mouse fibroblasts, which may be due to its ability to inhibit IGF-I production.
Chemical properties
Technical inquiry about: 3D-TTA74043 BMS 536924
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