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Product Information
BMS-554417 is a peptide inhibitor that binds to the receptor of the protein tyrosine phosphatase 1B (PTP1B). BMS-554417 is a potent inhibitor of PTP1B, with IC50 values in the low nanomolar range. The binding site on PTP1B has been mapped to a region between residues T478 and V480. BMS-554417 has been shown to activate the G protein pathway in human neutrophils, suggesting that it may have therapeutic potential for disorders such as chronic inflammation and atherosclerosis.
Chemical properties
Technical inquiry about: 3D-TTA74142 BMS-554417
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