BMS-554417

CAS: 468741-42-6

Ref. 3D-TTA74142

Product Information

• Name: BMS-554417
• Brand: Biosynth
• Description: BMS-554417 is a peptide inhibitor that binds to the receptor of the protein tyrosine phosphatase 1B (PTP1B). BMS-554417 is a potent inhibitor of PTP1B, with IC50 values in the low nanomolar range. The binding site on PTP1B has been mapped to a region between residues T478 and V480. BMS-554417 has been shown to activate the G protein pathway in human neutrophils, suggesting that it may have therapeutic potential for disorders such as chronic inflammation and atherosclerosis.

Chemical properties

• Molecular weight: 532 g/mol
• Formula: C₂₈H₃₀ClN₇O₂
• Purity: Min. 95%