4-Aminoisophthalonitrile
CAS: 19619-22-8
Ref. 3D-UAA61922
1g | Discontinued | ||
5g | Discontinued | ||
10g | Discontinued | ||
25g | Discontinued | ||
100mg | Discontinued | ||
500mg | Discontinued |
Product Information
- 1,3-Benzenedicarbonitrile, 4-amino-
- 1-Amino-2,4-dicyanobenzene
- 4-Amino-1,3-benzenedicarbonitrile
- 4-Aminobenzene-1,3-Dicarbonitrile
- Isophthalonitrile, 4-amino-
4-Aminoisophthalonitrile (4AI) is an anticancer agent that has been shown to be effective in the treatment of colorectal adenocarcinoma. It is a crystalline solid that can be obtained through the reaction of 4-aminobenzamide and nitrous acid. 4AI exhibits anticancer activity by inhibiting the growth of cancer cells, which may be due to its ability to inhibit protein synthesis by binding to the ribosomes in these cells. 4AI also binds to sulfoxide groups on proteins, resulting in changes in their conformation and inhibiting DNA replication and repair. This chemical has antibacterial properties, which are likely due to its ability to inhibit bacterial cell growth by interfering with protein synthesis. 4AI is acetylated at position 2 or 3 and formylated at position 2 or 3, depending on whether it is synthesized from 2-amino-5-nitrobenzamide or 5-amino