Product Information
1-Cyclopropylurea is a synthetic anticancer drug that was originally developed as an antihypertensive agent. It has been shown to have inhibitory effects on cancer cells and inflammatory diseases, including cyclic nucleotide phosphodiesterase (cNPD) and b-raf. 1-Cyclopropylurea also inhibits the synthesis of epoxyeicosatrienoic acids (EETs) in vitro, suggesting that it may be useful for the treatment of cardiovascular diseases such as hypertension.
1-Cyclopropylurea has been shown to inhibit cell proliferation in culture by causing G2/M phase arrest and apoptosis. The mechanism of action of 1-cyclopropylurea is not well understood, but it has been suggested that the drug prevents the phosphorylation of b-raf, which prevents the activation of mitogen activated protein kinases (MAPKs).
Chemical properties
Technical inquiry about: 3D-UAA75764 1-Cyclopropylurea
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