Protostemotinine
CAS: 169534-85-4
Ref. 3D-UGA53485
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10mg | To inquire | ||
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50mg | To inquire |
Product Information
- (3S,11S,11aS)-3'-Methoxy-4',9-dimethyl-3-[(2S,4S)-4-methyl-5-oxotetrahydrofuran-2-yl]-2,3,5,6,7,8-hexahydro-1H,5'H,10H-spiro[cyclopenta[b]pyrrolo[1,2-a]azepine-11,2'-furan]-5',10-dione
- spiro[1H-cyclopenta[b]pyrrolo[1,2-a]azepine-11(10H),2'(5'H)-furan]-5',10-dione, 2,3,5,6,7,8-hexahydro-3'-methoxy-4',9-dimethyl-3-[(2S,4S)-tetrahydro-4-methyl-5-oxo-2-furanyl]-, (3S,11S,11aS)-
Protostemotinine is a sesquiterpene with a molecular weight of 256.2 Da. It has been found in the tuberosa family, which includes plants such as the protostemonine-rich tuberosa and the amino acid glutamate-rich bamboo shoots. Protostemotinine can be analyzed by spectroscopic data analysis, liquid chromatography/electrospray ionization, or matrix effect methods. Protostemotinine is metabolized by cytochrome P450 enzymes and has been shown to have pharmacokinetic properties in rats. The main metabolic pathway is hydroxylation followed by conjugation with glucuronic acid or sulfate, although other metabolites have also been detected.
Protostemotinine has been shown to inhibit angiostrongylus cantonensis and rhizomes in vitro.
Chemical properties
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