Indirubin-5-sulfonate

CAS: 244021-67-8

Ref. 3D-UJA02167

Product Information

• Name: Indirubin-5-sulfonate
• Brand: Biosynth
• Description: Indirubin-5-sulfonate is a molecule that inhibits the activity of the protein kinase glycogen synthase kinase-3 (GSK-3). It binds to the GSK-3 enzyme and prevents it from phosphorylating glycogen synthase, which leads to inhibition of glycogen synthesis. The binding also leads to activation of caspases, which are proteins involved in apoptotic cell death. Indirubin-5-sulfonate has been shown to inhibit cancer growth in human cancer cells, including colon cancer and myeloid leukemia cells. This drug is a potential drug target for cancer therapy.

Chemical properties

• Molecular weight: 342.3 g/mol
• Formula: C₁₆H₁₀N₂O₅S
• Purity: Min. 95%