Product Information
Name:JNK Inhibitor VIII
Brand:Biosynth
Description:JNK inhibitor VIII is a potent, selective and cell-permeable JNK inhibitor that is effective in inhibiting the activation of pro-inflammatory genes. It has been shown to inhibit the proliferation and induce apoptosis in leukemia cells, as well as blocking the growth of primary human prostate cancer cells. JNK inhibitor VIII blocks ubiquitin ligases involved in protein degradation and mitochondrial membrane potential, which induces reactive oxygen species (ROS) production by mitochondria. This leads to an increase in cytosolic Ca2+, c-jun phosphorylation, and potential drug target for cancer therapy.
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Chemical properties
Molecular weight:356.38 g/mol
Formula:C18H20N4O4
Purity:Min. 95%
Technical inquiry about: JNK Inhibitor VIII
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