Product Information
Name:LY2857785
Brand:Biosynth
Description:LY2857785 is a potent and selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6). It inhibits the proliferation of cancer cells by interfering with cellular organelles, such as the mitochondria. LY2857785 has been shown to potently inhibit the proliferation of lymphocytic leukemia and fibrolamellar carcinoma cells. Inhibition of CDK4/6 activity leads to a decrease in transcriptional regulation, which may be due to an inhibition of cyclin D1 expression. The mechanism studies revealed that LY2857785 synergistically interacts with a number of inflammatory bowel disease drugs, including thalidomide and 5-aminosalicylic acid. This drug is effective against chronic lymphocytic leukemia at doses lower than those required for cancer treatment, making it a potential candidate for the prevention or treatment of this disease.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:448.6 g/mol
Formula:C26H36N6O
Purity:Min. 95%
Technical inquiry about: LY2857785
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.