Product Information
- 2-(4-methoxyphenyl)-1-{[5-(2-nitrophenyl)furan-2-yl]methyl}pyrrolidine
iST2-1 is a regulatory protein that may play an important role in the pathogenesis of inflammatory bowel disease (IBD). It has been shown to be over-expressed in IBD patients and animal models, which may lead to increased levels of inflammatory cytokines and chemokines. The pharmacokinetic properties of iST2-1 are not fully understood, but it appears to have a short half-life and low bioavailability. In vivo toxicity studies have shown that this molecule has no effect on cardiac function or hematopoietic cells. IBD patients with elevated levels of iST2-1 show higher plasma concentrations of this protein than those without IBD. This suggests that monitoring the plasma concentration of iST2-1 could be used as a biomarker for bowel disease or other inflammatory diseases.
Chemical properties
Technical inquiry about: 3D-UQB15802 iST2-1
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