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Product Information
Nicotinic acid 3-hydroxylase (NIC3) is a plant enzyme that catalyzes the conversion of 3-hydroxyl-anthranilic acid to nicotinic acid. It is found in higher plants and is involved in the biosynthesis of nicotinamide adenine dinucleotide phosphate (NADP) and nicotinate adenine dinucleotide phosphate (NADPH). It has also been shown to have anti-cancer properties, which may be due to its ability to inhibit protein synthesis. NIC3 is important for the production of NADPH, which is essential for the reduction of hydrogen peroxide and other reactive oxygen species, as well as for the demethylation of DNA. The activity of NIC3 can be inhibited by structurally similar molecules such as 3-hydroxyanthranilic acid.
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Chemical properties
Technical inquiry about: 3D-UUA83067 NIC3
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