Product Information
AMG 853 is a molecule that inhibits the activity of the enzyme Crth2, which plays a key role in calcium binding and release. AMG 853 has been shown to be safe and effective in the treatment of allergic and inflammatory diseases. The drug's mechanism of action is not fully understood, but it may work by preventing calcium from being released from cells. This would prevent the release of pro-inflammatory substances such as histamine, which are released by mast cells when they bind to IgE antibodies on their surface. AMG 853 has been shown to significantly reduce symptoms in patients with chronic urticaria (hives) over a four-week period without any side effects.
Chemical properties
Technical inquiry about: 3D-UWB48324 AMG 853
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