Product Information
- 8-Chloro-2-[(2S)-pyrrolidin-2-yl]-1H-[1]benzofuro[3,2-d]pyrimidin-4-one
XL413 is a novel small molecule that inhibits the replication of HIV-1. It has been shown to be effective in inhibiting replication of HIV-1 in both fetal bovine and human cells, with no toxicity for primary cells or prostate cancer cells. XL413 blocks cellular organelle replication by inhibiting lipid kinase, which is required for the production of phospholipids and subsequent liposome formation. XL413 also inhibits autophagy induction, which may contribute to its antiviral activity. This drug has shown efficacy in reducing ischemic brain damage as well as improving survival rates in pediatric patients with leukemia.
Chemical properties
Technical inquiry about: 3D-UWB55838 XL413
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