Product Information
Name:Aflutinib
Brand:Biosynth
Description:Aflutinib is a potent and selective inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase. Aflutinib was developed by Pfizer and is currently in phase II clinical trials for cancer treatment. This drug has been shown to be effective against cancers that overexpress EGFR, including lung cancer, pancreatic cancer, breast cancer, colorectal cancer, and head-and-neck cancers. The mechanism of action is inhibition of DNA synthesis by blocking the phosphorylation of tyrosine residues on the EGFR receptor. Aflutinib also binds to mesenchymal markers expressed at high levels in many cancers. This binding inhibits the activation of downstream signaling pathways such as RAS/RAF/MEK/ERK and PI3K/AKT pathways, leading to cell death.
Aflutinib has been shown to cause toxic epidermal necrolysis in some patients with
Aflutinib has been shown to cause toxic epidermal necrolysis in some patients with
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:568.6 g/mol
Formula:C28H31F3N8O2
Purity:Min. 95%
Technical inquiry about: Aflutinib
Please use instead the cart to request a quotation or an order
If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages.