Dilazep dihydrochloride

CAS: 20153-98-4

Ref. 3D-VAA15398

Product Information

• Name: Dilazep dihydrochloride
• Synonyms: 1,4-Bis(3-(3,4,5-trimethoxybenzoyloxy)-propyl)perhydro-1,4-diazepine dihydrochloride, 1,4-Bis{3-[(3,4,5-Trimethoxybenzoyl)Oxy]Propyl}-1,4-Diazepanediium Dichloride, 1,4-Diazepane-1,4-Diyldipropane-3,1-Diyl Bis(3,4,5-Trimethoxybenzoate), 1H-1,4-Diazepine, benzoic acid deriv., 1H-1,4-Diazepine-1,4(5H)-dipropanol, tetrahydro-, bis(3,4,5-trimethoxybenzoate) (ester), dihydrochloride, As 05, Asta C, Asta C 4898, Benzoic acid, 3,4,5-trimethoxy-, (tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester, dihydrochloride, Benzoic acid, 3,4,5-trimethoxy-, 1,1′-[(tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl] ester, hydrochloride (1:2), Benzoic acid, 3,4,5-trimethoxy-, diester with tetrahydro-1H-1,4-diazepine-1,4(5H)dipropanol, dihydrochloride, Ccris 3782, Comelian, Cormelian, Dilazep HCl, K-285, Labitan, N,N'-(Bis-omega-hydroxypropyl)homopiperazine 3,4,5-trimethoxybenzoate dihydrochloride, N,N'-Bis(3-(3,4,5-trimethoxybenzoyloxy)propyl)homopiperazine dihydrochloride, N,N′-Bis[3′-(3′′,4′′,5′′-trimethoxybenzoyloxy)propyl]hexahydro-1,4-diazepine dihydrochloride, Tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanol bis(3,4,5-trimethoxybenzoate) dihydrochloride

Description

Dilazep dihydrochloride is a p2y receptor antagonist that prevents the activation of these receptors by extracellular nucleotides. It is used to treat angina and other cardiovascular diseases, as well as for the prevention of myocardial infarctions. Dilazep dihydrochloride has been shown to inhibit adenosine transport and uridine uptake in hl-60 cells. This agent also inhibits binding of dipyridamole and adenosine to their respective receptors, which may be due to its ability to block calcium influx through the p2y receptor and subsequent activation of adenylate cyclase. The increased intracellular concentration of ATP has been shown to have a number of physiological effects, including inhibition of platelet aggregation, stimulation of glucose transport, and enhancement of energy metabolism.

• Brand: Biosynth

Chemical properties

• Molecular weight: 677.62 g/mol
• Formula: C₃₁H₄₄N₂O₁₀·2HCl
• Purity: Min. 95%