Product Information
- 2-Oxo-3-methylbutyric acid ethyl ester
- 3-Methyl-2-oxobutanoic acid ethyl ester
- Butanoic acid, 3-methyl-2-oxo-, ethyl ester
- Butyric acid, 3-methyl-2-oxo-, ethyl ester
- Ethyl 2-oxo-3-methylbutanoate
- Ethyl 2-oxo-3-methylbutyrate
- Ethyl 3-Methyl-2-Oxobutanoate
- Ethyl isopropylglyoxylate
- Ethyl α-ketoisovalerate
- Ketovaline ethyl ester
- See more synonyms
Ethyl 3-Methyl-2-oxobutyrate is an unsaturated carbonyl compound that has been found to have potent antimicrobial activity against gram-negative bacteria. The stereoselectivity of this molecule was studied in vitro using the linariifolia extract, which showed a preference for the (E) isomer. This molecule also has shown effectiveness against Pseudomonas aeruginosa and Actinomycetes. The compound’s pharmacokinetics were investigated in vivo with a model of mice, rats, and rabbits. It was found that ethyl 3-methyl-2-oxobutyrate had poor oral bioavailability but good tissue distribution and penetration into lung tissue.
The compound was also found to be thermophilic, meaning it can survive at high temperatures. This property may be useful for its potential use as an antimicrobial agent because many bacteria are heat sensitive and cannot grow at high temperatures.END>
Chemical properties
Technical inquiry about: 3D-VAA20124 Ethyl 3-Methyl-2-oxobutyrate
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