4-[(1E)-3-Hydroxyprop-1-en-1-yl]phenol

CAS: 20649-40-5

Ref. 3D-VAA64940

Product Information

• Name: 4-[(1E)-3-Hydroxyprop-1-en-1-yl]phenol
• Brand: Biosynth
• Description: 4-[(1E)-3-Hydroxyprop-1-en-1-yl]phenol (4-HP) is a natural compound that belongs to the group of polyphenols. It is one of the main constituents of the plant extract, which is obtained from leaves of the plant Ferula communis. 4-HP has been shown to have antiinflammatory activity by inhibiting prostaglandin synthesis in 3T3-L1 preadipocytes. The synergic effect can be explained by a combination of its antioxidant and antiinflammatory properties. In an analytical method, 4-HP was found to be present in ferulic acid and p-hydroxybenzoic acid. 4-HP also inhibits dna polymerase activity and rna synthesis at low concentration levels. The mechanism of action may be due to the inhibition of bacterial dna gyrase and topoisomerase I, leading to bacterial cell death.

Chemical properties

• Molecular weight: 150.17 g/mol
• Formula: C₉H₁₀O₂
• Purity: Min. 95%