Product Information
- 1-(p-Bromophenyl)-3-methylurea
- 3-(p-Bromophenyl)-1-methylurea
- Urea, N-(4-bromophenyl)-N′-methyl-
- N-(4-Bromophenyl)-N′-methylurea
- Urea, 1-(p-bromophenyl)-3-methyl-
1-(4-Bromophenyl)-3-methylurea is a nitrosourea that has been shown to be carcinogenic in experiments. It is an alkylating agent that may also have genotoxic properties. 1-(4-Bromophenyl)-3-methylurea can react with DNA, forming DNA adducts. This chemical is a potent inhibitor of the enzyme nitrite reductase, which reduces nitrite to nitric oxide and water. Nitric oxide is important for blood vessel dilation and vasodilation, as well as the regulation of vasoconstriction. The inhibition of this enzyme leads to increased blood pressure by blocking these effects. 1-(4-Bromophenyl)-3-methylurea is commonly used in the laboratory to induce papillomas on the skin of animals or fish, as well as carcinogenic activity in vitro.
Chemical properties
Technical inquiry about: 3D-VAA68007 1-(4-Bromophenyl)-3-methylurea
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