Product Information
- 5-Hydroxy-4,6-dimethylpyrimidine
- 5-Pyrimidinol, 4,6-Dimethyl-
4,6-Dimethylpyrimidin-5-ol (4,6-DMP) is a small molecule that is an immunomodulatory agent. It has been shown to have immunomodulatory effects on cells in vitro and in vivo. 4,6-DMP binds to the lipid bilayer of cell membranes and inhibits the activity of phosphoinositide 3-kinase, which results in changes in the intracellular concentration of calcium ions. This leads to an increase in cytokine production by T cells and B cells, as well as an increase in IgG production by plasma cells. Kinetic constants for the reactions of 4,6-DMP with various chemical moieties have been reported. These constants are useful for determining rates of reaction with other chemicals and can be used to determine mechanisms for 4,6-DMP’s antitumor activity.
Chemical properties
Technical inquiry about: 3D-VCA34538 4,6-Dimethylpyrimidin-5-ol
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