E6446 (dihydrochloride)
CAS: 1345675-25-3
Ref. 3D-VDC67525
| 2mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
E6446 is a dihydrochloride salt that inhibits the proteolytic activity of cathepsin B, an enzyme that may play a role in the degradation of extracellular matrix and other proteins. E6446 has been shown to inhibit the expression of inflammatory cytokines such as interleukin-1β, interleukin-6, and tumor necrosis factor alpha. This drug also has antiviral properties because it can inhibit the release of virus from infected cells by blocking activation of toll-like receptor 4. It has been shown to be effective against viruses such as influenza A virus and herpes simplex virus type 2. E6446 has been found to be safe for use in human clinical trials with no significant side effects reported.
Chemical properties
Technical inquiry about: 3D-VDC67525 E6446 (dihydrochloride)
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