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Raf1 Kinase Inhibitor I
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Raf1 Kinase Inhibitor I

CAS: 220904-83-6

Ref. 3D-VIA90483

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Estimated delivery in United States, on Thursday 16 Jan 2025

Product Information

Name:
Raf1 Kinase Inhibitor I
Synonyms:
  • (3Z)-3-[(3,5-dibromo-4-hydroxyphenyl)methylidene]-5-iodo-1,3-dihydro-2H-indol-2-one
  • 2H-Indol-2-one, 3-[(3,5-dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-
  • 3-(3,5-Dibromo-4-Hydroxybenzylidene)-5-Iodoindolin-2-One
  • 3-(3,5-Dibromo-4-hydroxybenzylidene)-5-iodo-1,3-dihydroindol-2-one
  • 3-[(3,5-Dibromo-4-hydroxyphenyl)methylene]-1,3-dihydro-5-iodo-2H-indol-2-one
  • Gw-5074
  • Gw5074
  • MG 005
Description:

Raf1 Kinase Inhibitor I is an inhibitor of mitogen-activated protein kinase (MAPK) and it inhibits Raf1 kinase activity. It has been shown to inhibit the production of inflammatory cytokines, such as colony-stimulating factor and chemokines, in bronchial epithelial cells. Raf1 Kinase Inhibitor I is also a potent inhibitor of neutrophil recruitment by blocking the activation of NF-κB. Raf1 Kinase Inhibitor I was shown to have antitumor activity in some cell lines and may be useful for the treatment of cancer or inflammatory diseases.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
520.94 g/mol
Formula:
C15H8Br2INO2
Purity:
Min. 95%
MDL:
Melting point:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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