FPS-ZM1

CAS: 945714-67-0

Ref. 3D-VMB71467

Product Information

• Name: FPS-ZM1
• Brand: Biosynth
• Description: FPS-ZM1 is a small molecule drug with immunomodulatory and anti-inflammatory properties. It was originally synthesized as an inhibitor of the transcriptional regulator HMG-BOX, which is found in the promoters of genes involved in neuronal death, inflammation, and autoimmune diseases. FPS-ZM1 inhibits the transcriptional regulator HMG-BOX by binding to it, thereby preventing it from interacting with its DNA target. This inhibition leads to decreased expression of proinflammatory genes. The effects of FPS-ZM1 on inflammatory responses have been demonstrated in vitro and in vivo using human cells. In addition, FPS-ZM1 has been shown to inhibit Toll-like receptor (TLR) signaling pathways that are activated by lipopolysaccharide (LPS).

Chemical properties

• Molecular weight: 327.85 g/mol
• Formula: C₂₀H₂₂ClNO
• Purity: Min. 95%