Avatrombopag

CAS: 570406-98-3

Ref. 3D-VXA40698

Product Information

• Name: Avatrombopag
• Synonyms: 1-(3-Chlor-5-{[4-(4-chlor-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-1,3-thiazol-2-yl]carbamoyl}-2-pyridinyl)-4-piperidincarbons�ure [German], 1-(3-Chloro-5-{[4-(4-Chlorothiophen-2-Yl)-5-(4-Cyclohexylpiperazin-1-Yl)Thiazol-2-Yl]Carbamoyl}Pyridin-2-Yl)Piperidine-4-Carboxylic Acid, 1-(3-Chloro-5-{[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-1,3-thiazol-2-yl]carbamoyl}-2-pyridinyl)-4-piperidinecarboxylic acid, 1-[3-Chloro-5-[[4-(4-chlorothiophen-2-yl)-5-(4-cyclohexylpiperazin-1-yl)thiazol-2-yl]carbamoyl]-2-pyridyl]piperidine-4-carboxylic acid, 1-[3-Chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbonyl]-2-pyridinyl]-4-piperidinecarboxylic acid, 4-Piperidinecarboxylic acid, 1-[3-chloro-5-[[[4-(4-chloro-2-thienyl)-5-(4-cyclohexyl-1-piperazinyl)-2-thiazolyl]amino]carbonyl]-2-pyridinyl]-, Akr 501, As 1670542, Doptelet, E-5501

Description

Avatrombopag is a drug that belongs to the class of thrombopoietin receptor agonists. It stimulates the production of platelets in patients with thrombocytopenia by binding to and activating the thrombopoietin receptor, which is found on the surface of bone marrow cells. Avatrombopag has been shown to be effective in reducing the incidence of bleeding episodes in these patients. The clinical relevance of avatrombopag has been shown using monoclonal antibodies in human and animal studies. There are no known toxic effects associated with avatrombopag treatment, as it does not cross the blood-brain barrier or enter into breast milk.

• Brand: Biosynth

Chemical properties

• Molecular weight: 649.65 g/mol
• Formula: C₂₉H₃₄Cl₂N₆O₃S₂
• Purity: Min. 95%