Desmethyl dabrafenib

CAS: 1195765-47-9

Ref. 3D-VXB76547

Product Information

• Name: Desmethyl dabrafenib
• Brand: Biosynth
• Description: Desmethyl dabrafenib is a synthetic drug product that is used in research and development. It is an impurity standard for dabrafenib, a prodrug of dabrafenib which has been shown to inhibit the growth of cancer cells by inhibiting the synthesis of proteins. Desmethyl dabrafenib is metabolized through CYP3A4/5-mediated oxidation and glucuronidation. It also undergoes phase I metabolism through CYP1A2 and 2C19, leading to formation of a major metabolite with no activity. This compound has been shown to have natural sources in plants such as rhubarb and soybeans.

Chemical properties

• Molecular weight: 505.50 g/mol
• Formula: C₂₂H₁₈F₃N₅O₂S₂
• Purity: Min. 95%