Dequalinium chloride

CAS: 522-51-0

Ref. 3D-W-105841

Product Information

• Name: Dequalinium chloride
• Synonyms: 1,1'-Decamethylenebis(4-aminoquinaldinium)dichloride, 1,1'-Decane-1,10-Diylbis(4-Amino-2-Methylquinolinium) Dichloride, 1,1′-Decamethylenebis[4-aminoquinaldinium chloride], Badq 10, Baqd 10, Decamethylenebis[4-aminoquinaldinium chloride], Decamine, Decamine (pharmaceutical), Decatylen, Dekadin, Dekamiln, Dekamin, Dequacets, Dequadin, Dequadin chloride, Dequafungen, Dequalinum Chloride, Dequavagyn, Dequavet, Efisol, Eriosept, Evazol, Fluomizin, Fluomycin N, Grocreme, Ivazil, Labosept, Ldn 0096422, NSC 166454, Optipect, Oralgol, Phylletten, Polycidine, Quinaldinium, 1,1′-decamethylenebis[4-amino-, dichloride, Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, chloride (1:2), Quinolinium, 1,1′-(1,10-decanediyl)bis[4-amino-2-methyl-, dichloride, Rumilet, Sanoral, Sentril, Sorot

Description

Dequalinium chloride is a novel, broad spectrum antimicrobial agent with a mechanism of action that inhibits the mitochondria-dependent respiratory chain. Studies have shown that it inhibits the growth of resistant microorganisms in cell-based experiments and in bacterial infections. Dequalinium chloride also has cytopathic effects on thp-1 cells, which are specific for Mycobacterium tuberculosis. In addition to inhibiting mitochondria-dependent respiration, this compound also increases acetylcholine receptor sensitivity in A549 lung cancer cells. Dequalinium chloride is a quaternary ammonium cation and has been shown to be effective against clinical isolates and inhibitory concentrations of a variety of virus species, including human rhinovirus (HRV) and Coxsackie virus type B4 (CoxB4).

• Brand: Biosynth

Chemical properties

• Molecular weight: 527.57 g/mol
• Formula: C₃₀H₄₀Cl₂N₄
• Purity: Min. 95.0 Area-%