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N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine
CAS: 100898-63-3
Ref. 3D-W-200637
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Product Information
- N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxycytidine
- N4-Acetyl-2'-deoxy-5'-O-DMT-D-cytidine
- N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine
- 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine (synthetic)
- Dmt-Ac-dC
- 5'-DMTr-N4-acetyl-2'-deoxycytidine
N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine is a novel anticancer agent that is modified with a phosphoramidite. It is a nucleoside analog that selectively inhibits DNA polymerases and RNA polymerases, and therefore prevents the synthesis of DNA and RNA. N4-Acetyl-2'-deoxy-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-cytidine has been shown to be highly active against various cell lines in vitro, including human leukemia cells (HL60), human prostate cancer cells (PC3), human breast cancer cells (MCF7), and human mammary tumor cells (HTB6). This compound has also been shown to have antiestrogenic activity in vivo.
Chemical properties
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