Product Information
1-phenyl-4-(prop-2-yn-1-yl)piperazine is a dihalogenated compound with an azide substituent. It was first synthesized from potassium t-butoxide and cyclopropane in the presence of acetic acid. The synthesis was then completed by adding the 1,4-dihaloethane to the intermediate. This reaction proceeds via a sequential, two step cycloaddition reaction that produces a triazole ring system. This compound has been shown to be effective against Giardia lamblia trophozoites and Coccidia trophozoites. 1-phenyl-4-(prop-2-yn-1-yl)piperazine also has antihistamine activity, which may be due to its inhibition of histamine release from mast cells or basophils. It is also capable of inhibiting proliferation of human prostate cancer cells in culture at low concentrations and can induce apoptosis
Chemical properties
Technical inquiry about: 3D-WAA05745 1-phenyl-4-(prop-2-yn-1-yl)piperazine
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