5-Amino-1-cyclohexyl-1H-pyrazole-4-carbonitrile

CAS: 21254-04-6

Ref. 3D-WAA25404

Product Information

• Name: 5-Amino-1-cyclohexyl-1H-pyrazole-4-carbonitrile
• Brand: Biosynth
• Description: 5-Amino-1-cyclohexyl-1H-pyrazole-4-carbonitrile (5ACPC) is a ligand that is used in cancer therapy. It binds to the uptake mechanisms of cancer cells and prevents the uptake of amino acids, which are essential for cell growth and proliferation. Treatment with 5ACPC has been shown to inhibit cancer cell growth in vitro and in vivo by interfering with cellular processes such as transcription, DNA replication, and protein synthesis. 5ACPC has also been shown to be an immunoreceptor ligand that binds to the CD3 receptor on T cells, preventing activation and proliferation of these cells. 5ACPC can also act as a bispecific antibody that binds to two different antigens (e.g., tumor antigen and immune system antigen). This binding can lead to the destruction of cancer cells by complement mediated lysis or antibody dependent cell mediated cytotoxicity (ADCC).

Chemical properties

• Molecular weight: 190.25 g/mol
• Formula: C₁₀H₁₄N₄
• Purity: Min. 95%