Product Information
- (2R*,3R*)-2,3-Dimethyloxirane
- Butane, 2,3-epoxy-, trans-
- NSC 24244
- Oxirane, 2,3-dimethyl-, (2R,3R)-rel-
- Oxirane, 2,3-dimethyl-, trans-
- rel-(2R,3R)-2,3-Dimethyloxirane
- trans-2,3-Butene oxide
- trans-2,3-Butylene oxide
- trans-2-Butene oxide
- trans-2-Butylene oxide
- See more synonyms
- trans-beta-Butylene oxide
Pinostrobin is a chalcone that has been shown to inhibit the growth of certain fungi by inhibiting the enzyme activities involved in cell walls synthesis. Pinostrobin is converted to trans-2,3-epoxybutane (EPB) by intramolecular hydrogen transfer. EPB has an antifungal activity that is stronger than pinostrobin and it can be used as a fungicide against certain fungal diseases. This compound may also have anticancer effects. EPB binds to mammalian cells by forming hydrogen bonds with the amino acids, glutamine and asparagine, which are found in abundance on the surface of mammalian cells. EPB's binding to these amino acids prevents the formation of hydrogen bonds between glutamine and asparagine residues on adjacent protein molecules, leading to destabilization of the cell membrane and cell death.
Chemical properties
Technical inquiry about: 3D-WAA49063 trans-2,3-Epoxybutane
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