Product Information
Name:N-(4-Chlorophenyl)-2-hydroxyacetamide
Brand:Biosynth
Description:4-Chloro-N-(2-hydroxyacetyl)aniline (NHA) is a metabolite of the anti-cancer drug piperonyl butoxide. It has been shown to inhibit the growth of tumor xenografts in mice, and may be an effective cancer treatment. The mechanism of NHA's inhibition of tumor growth is through its oxidative metabolites that induce DNA damage, leading to apoptosis. The production of these compounds is increased when it is incubated with α-tocopherol or rhesus monkeys, which suggests that they are conjugates with glucuronic acid. In humans, 4-chloro-NHA undergoes oxidation by dehydrogenases to form 4-chloroaniline and 2-(4-chlorophenoxy)-N-(2-hydroxyacetyl)acetic acid (4CPHAA). This last compound can be conjugated with either glutathione or glucuronic acid to form
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Chemical properties
Molecular weight:185.61 g/mol
Formula:C8H8ClNO2
Purity:Min. 95%
Technical inquiry about: N-(4-Chlorophenyl)-2-hydroxyacetamide
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