Product Information
2-(2-Bromophenyl)oxirane is a sulfinyl compound that is used in the synthesis of epipodophyllotoxins. It has been shown to react with an enolate of a malonate, forming a β-unsaturated lactone and a sulfinyl group. This reaction is regioselective, giving the desired epipodophyllotoxin with the sulfinyl group on the less hindered side of the molecule. The deuterated analogues of 2-(2-bromophenyl)oxirane can be prepared by substituting one or more hydrogens with deuterium atoms. These analogues are useful for studying conformational changes in molecules because they have different nuclear magnetic resonance (NMR) spectra from their non-deuterated counterparts. 2-(2-Bromophenyl)oxirane is also useful for synthesizing styrene derivatives such as ring-opened compounds.
Chemical properties
Technical inquiry about: 3D-WCA63651 2-(2-Bromophenyl)oxirane
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