Dimethyl 2-(Methoxymethylene)malonate

CAS: 22398-14-7

Ref. 3D-XAA39814

Product Information

• Name: Dimethyl 2-(Methoxymethylene)malonate
• Synonyms: 1,3-Dimethyl 2-(methoxymethylene)propanedioate, 1,3-Dimethyl 2-(methoxymethylidene)propanedioate, 2-(Methoxymethylene)Malonate, Dimethyl (Methoxymethylidene)Propanedioate, Dimethyl 2-(methoxymethylene)malonate, Dimethyl 2-(methoxymethylene)propanedioate, Dimethylmethoxymethylenmalonat, Malonic acid, (methoxymethylene)-, dimethyl ester, Methoxymethylenemalonic Acid Dimethyl Ester, Mmmm, NSC 131266, Propanedioic acid, (methoxymethylene)-, dimethyl ester, Propanedioic acid, 2-(methoxymethylene)-, 1,3-dimethyl ester

Description

Dimethyl 2-(methoxymethylene)malonate is a synthetic molecule that belongs to the class of organic compounds known as dialkylamino malonic esters. It has been shown to inhibit HIV integrase, an enzyme that is essential for HIV replication. Dimethyl 2-(methoxymethylene)malonate was synthesized in two steps from diethyl malonate and methoxyamine hydrochloride. The first step involved the reaction of diethyl malonate with methoxyamine hydrochloride in the presence of nitrobenzene to produce dimethyldiethoxymethoxymethoxymalonic acid methyl ester. The second step involved reacting this product with trimethylamine in the presence of potassium carbonate to produce dimethyl 2-(methoxymethylene)malonate.

• Brand: Biosynth

Chemical properties

• Molecular weight: 142.15 g/mol
• Formula: C₇H₁₀O₃
• Purity: Min. 95%