Daphnetin-8-methyl ether

CAS: 485-90-5

Ref. 3D-XD163676

Product Information

• Name: Daphnetin-8-methyl ether
• Synonyms: Hydrangetin, 2H-1-benzopyran-2-one, 7-hydroxy-8-methoxy-, 7-Hydroxy-8-methoxycoumarin

Description

Daphnetin-8-methyl ether is a coumarin derivative that has been shown to have antihepatitis activity in cell culture. The compound inhibits the secretion of interleukin-1β and TNF-α in response to lipopolysaccharide (LPS) stimulation, as well as the production of nitric oxide. Daphnetin-8-methyl ether also has an inhibitory effect on the growth of phytophthora megasperma and daphnetin-8-methyl ether can be used as a medicine for treating hepatitis. Daphnetin-8-methyl ether is active at an optimum pH range of 5.0-6.5, which is within the human body's physiological pH range.

• Brand: Biosynth

Chemical properties

• Molecular weight: 192.17 g/mol
• Formula: C₁₀H₈O₄
• Purity: Min. 95%
• InChI: InChI=1S/C10H8O4/c1-13-10-7(11)4-2-6-3-5-8(12)14-9(6)10/h2-5,11H,1H3
• InChI key: InChIKey=HAQWEMHXSIRYBE-UHFFFAOYSA-N
• SMILES: COc1c(O)ccc2ccc(=O)oc12