4-(Difluoromethoxy)benzamide

CAS: 147992-28-7

Ref. 3D-XFA99228

Product Information

• Name: 4-(Difluoromethoxy)benzamide
• Brand: Biosynth
• Description: 4-(Difluoromethoxy)benzamide is an intermediate in the synthesis of roflumilast, which is a drug used to treat asthma. This intermediate is produced by condensation of methoxybenzoic acid with benzaldehyde and hydrochloric acid. The product can be purified by recrystallization or by conversion to its n-oxide, which has advantages over the chloride form because it is easier to handle and has less impurities. 4-(Difluoromethoxy)benzamide can be used in the industrial production of roflumilast, as it reacts quickly and easily with other chemicals.

Chemical properties

• Molecular weight: 187.14 g/mol
• Formula: C₈H₇F₂NO₂
• Purity: Min. 95%