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Dec-poc pmpa
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Dec-poc pmpa

CAS: 1422284-17-0

Ref. 3D-XGC28417

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Estimated delivery in United States, on Friday 21 Jun 2024

Product Information

Name:
Dec-poc pmpa
Synonyms:
  • 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, 1-ethyl 9-(1-Methylethyl) ester, 5-oxide
  • 2,4,6,8-Tetraoxa-5-phosphanonanedioic acid, 5-[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]-, 1-ethyl 9-(1-methylethyl) ester, 5-oxide, (2E)-2-butenedioate (1:1)
Description:

Dec-poc pmpa is an oral prodrug that exhibits potent antiviral activity against HIV. It is rapidly converted to its active form, tenofovir alafenamide hemifumarate, in the presence of hydrochloric acid. Dec-poc pmpa has excellent pharmacokinetic properties, resulting in sustained plasma levels and enhanced bioavailability compared to other pharmaceutical preparations of tenofovir. This prodrug undergoes a phase transfer reaction in the body, allowing for efficient conversion to the active antiretroviral agent. Additionally, Dec-poc pmpa has been formulated to minimize impurities and contains an acid-binding agent to reduce potential renal biomarkers associated with tenofovir administration. Its mechanism of action involves inhibiting viral replication by targeting adenine residues in viral DNA synthesis.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
621.5 g/mol
Formula:
C22H32N5O14P
Purity:
Min. 95%
MDL:
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EINECS:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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