Pateamine A

CAS: 139220-18-1

Ref. 3D-XP183225

Product Information

• Name: Pateamine A
• Brand: Biosynth
• Description: Pateamine A is a natural product, specifically a marine macrolide, which is isolated from the marine sponge *Mycale* species. It functions as a potent modulator of translation initiation in eukaryotic cells. By targeting the eukaryotic initiation factor 4A (eIF4A), Pateamine A disrupts the assembly of the eIF4F complex, thereby inhibiting the initiation phase of protein synthesis. This disruption results in the downregulation of cap-dependent translation, impacting the production of proteins critical for cellular growth and survival.

Chemical properties

• Molecular weight: 555.77 g/mol
• Formula: C₃₁H₄₅N₃O₄S
• Purity: Min. 95%