Product Information
- O-Palmitoylseverine4- [4- [2- (Benzoylamino) ethyl] phenoxy] - 1- [(3
- 3- dimethyloxiranyl) methyl] - 2- methyl- 2- butenyl ester h exadecanoic acid
Severine is a natural product that is extracted from the leaves of Rutaceae. It has been shown to have anticancer properties against cholangiocarcinoma cells, which may be due to its ability to inhibit the proliferation and induce apoptosis in these cells. Severine is converted into severine palmitate by acetylation, forming a new molecule with antiproliferative activity. The chemical structure of severine palmitate consists of an apigenin-derived crenulata skeleton with a natural product flavone at C-6 and a diacetate ester at C-7. Severine palmitate has been shown to be effective against human cholangiocarcinoma cell lines in vitro, as well as in vivo when administered orally or intravenously.
Chemical properties
Technical inquiry about: 3D-XS161558 Severine palmitate
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