Dextran sulfate potassium salt
CAS: 39422-86-1
Ref. 3D-YD31035
1g | 136.00 € | ||
2g | 205.00 € | ||
5g | 330.00 € | ||
10g | 467.00 € | ||
25g | 814.00 € |
Product Information
Dextran sulphate is a dextran derivative whose ulcer (colitis) -causing properties were first reported in hamsters and extrapolated a few years later to mice and rats. The exact mechanisms through which dextran sulphate induces intestinal inflammation are unclear but may be the result of direct damage of the monolayer of epithelial cells in the colon, leading to the crossing of intestinal contents (for e.g. commensal bacteria and their products) into underlying tissue and therefore induction of inflammation. The dextran sulphate sodium-induced ulceration model in laboratory animals has some advantages when compared to other animal models of colitis due to its simplicity and similarities to human inflammatory bowel disease.
MW is in the range of 40,000Da
Chemical properties
Technical inquiry about: 3D-YD31035 Dextran sulfate potassium salt
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