Millewanin G
CAS: 874303-33-0
Ref. 3D-ZJB30333
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 25mg | To inquire | ||
| 50mg | To inquire |
Product Information
- 4H-1-Benzopyran-4-one, 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(2-hydroxy-3-methyl-3-butenyl)-8-(3-methyl-2-butenyl)-, (+)-
- (+)-3-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(2-hydroxy-3-methyl-3-buten-1-yl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(2-hydroxy-3-methyl-3-buten-1-yl)-8-(3-methyl-2-buten-1-yl)-, (+)-
Millewanin G is a prenyl flavonoid derivative with antioxidant effects. It has been shown to have potent inhibitory activity against the cellular activities of estrogen and anti-estrogenic effects in diabetic patients. Millewanin G has also been shown to reduce insulin resistance in mice, which may be due to its ability to inhibit the production of reactive oxygen species. Millewanin G is derived from the plant Ampelopsis japonica and has strong inhibitory activity against breast cancer cells and human leukemia cells. The molecular docking analysis showed that millewanin G binds to the protein insulin receptor substrate 1 (IRS-1) and inhibits its phosphorylation by inhibiting the hydrogen bond between IRS-1 and insulin receptor (IR).
Chemical properties
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