Millewanin G
CAS: 874303-33-0
Ref. 3D-ZJB30333
5mg | To inquire | ||
10mg | To inquire | ||
25mg | To inquire | ||
50mg | To inquire |
Product Information
Millewanin G is a prenyl flavonoid derivative with antioxidant effects. It has been shown to have potent inhibitory activity against the cellular activities of estrogen and anti-estrogenic effects in diabetic patients. Millewanin G has also been shown to reduce insulin resistance in mice, which may be due to its ability to inhibit the production of reactive oxygen species. Millewanin G is derived from the plant Ampelopsis japonica and has strong inhibitory activity against breast cancer cells and human leukemia cells. The molecular docking analysis showed that millewanin G binds to the protein insulin receptor substrate 1 (IRS-1) and inhibits its phosphorylation by inhibiting the hydrogen bond between IRS-1 and insulin receptor (IR).
Chemical properties
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