Product Information
STM2457 is a potent and selective activator of the human GABAA receptor. It binds to the central benzodiazepine binding site on the GABA-A receptor, thereby promoting the opening of chloride channels. This leads to hyperpolarization of the membrane, which decreases neuronal excitability. STM2457 has been shown to be an effective inhibitor of ion channels in mammalian cells and is used as a research tool for pharmacology and protein interactions.
Chemical properties
Technical inquiry about: 3D-ZZD66301 STM2457
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