BIS(TRIMETHYLSILYL)ACETYLENE

CAS: 14630-40-1

Ref. 3H-SIB1850.0

Product Information

• Name: BIS(TRIMETHYLSILYL)ACETYLENE
• Synonyms: 1,1′-(1,2-Ethynediyl)bis[1,1,1-trimethylsilane], 1,2-Bis(trimethylsilanyl)ethyne, 1,2-Bis(trimethylsilyl)acetylene, 1,2-Bis(trimethylsilyl)ethyne, 2,5-Disilahex-3-yne, 2,2,5,5-tetramethyl-, Bis(trimethylsilyl)ethyne, Bstma, Btmsa, Ethyne-1,2-Diylbis(Trimethylsilane), Silane, 1,1′-(1,2-ethynediyl)bis[1,1,1-trimethyl-, Silane, 1,2-ethynediylbis[trimethyl-, Trimethyl(2-trimethylsilylethynyl)silane, Bis(trimethylsilyl)acetylene

Description

Alkynylsilane Cross-Coupling Agent
The cross-coupling reaction is a highly useful methodology for the formation of carbon-carbon bonds. It involves two reagents, with one typically being a suitable organometallic reagent - the nucleophile - and the other a suitable organic substrate, normally an unsaturated halide, tosylate or similar - the electrophile.
Bis(trimethylsilyl)acetylene; Bis(trimethylsilyl)ethyne
Useful in Sonogashira cross-coupling reactionsVersatile reagent for introducing unsaturationUsed to prepare 1,2-bis(aryl)acetylenesReacts with internal acetylenes to form 1,2,4,5-tetrasubstituted benzenesUsed to prepare 4-alkynylthiazolesExtensive review of silicon based cross-coupling agents: Denmark, S. E. et al. "Organic Reactions, Volume 75" Denmark, S. E. ed., John Wiley and Sons, 233, 2011

• Brand: Gelest

Chemical properties

• Molecular weight: 170.4
• Formula: C₈H₁₈Si₂
• Purity: 97%
• Color/Form: Straw Liquid