t-BUTYLDIPHENYLCHLOROSILANE

CAS: 58479-61-1

Ref. 3H-SIB1968.0

Product Information

• Name: t-BUTYLDIPHENYLCHLOROSILANE
• Synonyms: (1,1-Dimethylethyl)diphenylsilyl chloride, (Chloro)(tert-butyl)diphenylsilane, 1,1′-[Chloro(1,1-dimethylethyl)silylene]bis[benzene], Benzene, 1,1'-[chloro(1,1-dimethylethyl)silylene]bis-, Chloro(1,1-dimethylethyl)diphenylsilane, Chlorodiphenyl-tert-butylsilane, Diphenyl-tert-butylsilyl chloride, Nsc 617386, Silane, Tert-Butyl-Diphenylchloro-, TBDPSCl, TDBPSCl, Terc-Butilclorodifenilsilano, t-Butylchlorodiphenylsilane, t-Butyldiphenylchlorosilane, tert-Butylchlordiphenylsilan, tert-Butylchlorodiphenylsilane, tert-Butyldiphenylchlorosilane, tert-Butyldiphenylsilyl chloride

Description

Phenyl-Containing Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
tert-Butyldiphenylchlorosilane; (1,1-Dimethylethyl)diphenylchlorosilane; tert-Butylchlorodiphenylsilane
Forms more stable ethers than TBS ethersUsed to protect phenols, amines, carboxylic acids, and amidesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

• Brand: Gelest

Chemical properties

• Molecular weight: 274.87
• Formula: C₁₆H₁₉ClSi
• Color/Form: Straw Liquid