CHLOROMETHYLDIMETHYLCHLOROSILANE

CAS: 1719-57-9

Ref. 3H-SIC2285.0

Product Information

• Name: CHLOROMETHYLDIMETHYLCHLOROSILANE
• Synonyms: CMDMCS, (Chloromethyl)chlorodimethylsilane, (Chloromethyl)dimethylsilyl chloride, Chloro(chloromethyl)dimethylsilane, Chlorodimethyl(chloromethyl)silane, Chloromethyldimethylchlorosilane, Cmdmcs, Dimethyl(chloromethyl)chlorosilane, Dimethylchloro(chloromethyl)silane, LS 230 (silane), Ls 230, Silane, chloro(chloromethyl)dimethyl-
• CAS: 1719-57-9

Description

Specialty Silicon-Based Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Chloromethyldimethylchlorosilane; (Chlorodimethylsilyl)chloromethane; Chloro(chloromethyl)dimethylsilane; CMDMCS
Can form cyclic products with appropriate 1,2-difunctional substratesUsed in analytical applications for greater ECD detectabilitySummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

• Brand: Gelest

Chemical properties

• Molecular weight: 143.09
• Formula: C₃H₈Cl₂Si
• Purity: 97%
• Color/Form: Straw Liquid