1-METHOXY-1-(TRIMETHYLSILOXY)-2-METHYL-1-PROPENE

CAS: 31469-15-5

Ref. 3H-SIM6496.0

Product Information

• Name: 1-METHOXY-1-(TRIMETHYLSILOXY)-2-METHYL-1-PROPENE
• Synonyms: METHYL(TRIMETHYLSILYL)DIMETHYLKETENE ACETAL
• Brand: Gelest
• Description: Trimethylsilyl Blocking AgentUsed as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.1- Methoxy-1-trimethysiloxy-2-methyl-1-propene; Methyl(trimethylsilyl)dimethylketene acetal; 1-Methoxy-2-methyl-1-(trimethylsiloxy)propeneUsed for silylation of acids, alcohols, thiols, amides and ketonesNafion SAC-13 has been shown to be a recyclable catalyst for the trimethylsilylation of primary, secondary, and tertiary alcohols in excellent yields and short reaction timesSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

Chemical properties

• Molecular weight: 174.31
• Formula: C₈H₁₈O₂Si
• Purity: 97%
• Color/Form: Straw Liquid