TRIISOPROPYLCHLOROSILANE

CAS: 13154-24-0

Ref. 3H-SIT8384.0

Product Information

• Name: TRIISOPROPYLCHLOROSILANE
• Synonyms: TIPS-CHLORIDE, Chloro(Tripropan-2-Yl)Silane, Chlorotriisopropylsilane, Chlorotriisopropylsilane, Wacker Quality, Chlorotris(1-methylethyl)silane, Silane Ip3, Silane, Chlorotris(1-Methylethyl)-, Silane, chlorotriisopropyl-, Tipsc, Tipsci, Triisopropyl Chloro Silane, Triisopropylchlorosilane (TIPSCl), Triisopropylchlorosilane, Redistilled, Triisopropylsilyl Chloride, Triisopropylsilyl Cloride, Triisoprpylchlorosilane, Trimethylsilyl Trifluoromethane Sulphonate, tris-Isopropylchlorosilane, Triisopropylchlorosilane, Triisopropylchlorosilane

Description

Trialkylsilyl Blocking Agent
Used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. The tolerance of silylated alcohols to chemical transformations summary is presented in Table 1 of the Silicon-Based Blocking Agents brochure.
Triisopropylchlorosilane; Chlorotriisopropylsilane; TIPS-Cl
TIPS ethers more stable than TBS ethersProtects carboxylic acidsUsed in synthesis of free-4-hydroxylhexopyranosesSteric bulk allows for selective silylation of compounds with more than one hydroxyl groupSummary of selective deprotection conditions is provided in Table 7 through Table 20 of the Silicon-Based Blocking Agents brochure

• Brand: Gelest

Chemical properties

• Molecular weight: 192.81
• Formula: C₉H₂₁ClSi
• Purity: 97%
• Color/Form: Liquid