86-MM0154.05-0025 - bendamustine-ethyl-ester | 87475-54-5
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Bendamustine Ethyl Ester
CAS:Controlled ProductImpurity Bendamustine USP Related Compound I
Stability Moisture sensitive
Applications Bendamustine Ethyl Ester is an impurity of Bendamustine (B132500), which is used as an anticancer drug.
References Bremer, K., et al.: Tumordiagn. Ther., 17, 1 (1996); Barman Balfour, J.A., et al.: Drugs, 61, 631 (2001)Formula:C18H25Cl2N3O2Color and Shape:Light Yellow To BeigeMolecular weight:386.32Bendamustine ethyl ester
CAS:Bendamustine ethyl ester is a potent inhibitor of kinases in human urine. It is used in the treatment of cancer and tumors, as it has been shown to induce apoptosis in cancer cells. This drug is an analog of donepezil and has been found to inhibit several kinases, including protein kinase C and mitogen-activated protein kinase. Bendamustine ethyl ester has demonstrated anticancer activity against Chinese hamster ovary (CHO) cells and other cancer cell lines. It works by inhibiting DNA synthesis and inducing DNA damage, leading to cell cycle arrest and apoptosis. Bendamustine ethyl ester may be used in combination with other inhibitors for enhanced efficacy against cancer cells.Formula:C18H25Cl2N3O2Purity:Min. 95%Molecular weight:386.3 g/molBendamustine Related Compound I (Ethyl 4-{5-[bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazol-2-yl}butanoate)
CAS:Heterocyclic compounds with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C18H25Cl2N3O2Color and Shape:White SolidMolecular weight:385.13238Bendamustine USP Related Compound I
CAS:Formula:C18H25Cl2N3O2Color and Shape:White To Off-White SolidMolecular weight:386.32
